条件を付加する。利用者は事前に寄託者の提供承諾書を得る。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。Biochem. Biophys. Res. Commun., 321, 275-279 (2004).<br>非営利機関が非営利目的の教育・研究用に用いる場合以外は、大阪大学と別途MTAを締結すること（https://www.ccb.osaka-u.ac.jp/en/）。5年経過後も使用を希望するときは改めて寄託者から承諾を得るものとする。 Osaka Univ. Carrier x Noncarrier [C57BL/6NCrSlc] Carrier x Noncarrier [C57BL/6NCrSlc] B6.Cg-Tg(CAG-Cre)CZ-MO2Osb B6.Cg-Tg(CAG-Cre)CZ-MO2Osb Necessary documents for ordering:<ol><li>Approval form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx">English</A>)</li><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>CAGGS MTA (<A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/CAGGS_MTA.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol><A HREF="https://egr.biken.osaka-u.ac.jp/achievement/bio_resources" target="_blank">Lab HP</A> The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biochem. Biophys. Res. Commun., 321, 275-279 (2004).RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University (https://www.ccb.osaka-u.ac.jp/en/). The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again. CAG-cre CAG-cre Cre/loxP system CAGプロモーターの下流に、Cre組み換え酵素遺伝子を持つ。全身でcreを発現し、条件的遺伝子組み換えに利用できる。 岡部　勝 Masaru OKABE true <a href='https://brc.riken.jp/mus/pcr01828'>Genotyping protocol -PCR-</a> Developed by Masaru Okabe, Research Institute for Microbial Diseases, Osaka University in 2003. The transgene was injected into the pronuclei of B6D2F2 fertilized eggs. The mice were backcrossed C57BL/6N. These transgenic mice express Cre recombinase gene under the control of CAG promoter. This strain can be used to make an inducible knock-out by crossing with the other genetically-engineered mice that have a loxP site-flanked sequence of interest. The recombination occurs in all over the body. 大阪大学微生物病研究所・岡部　勝先生（2003）。トランスジーンをB6D2F2受精卵へインジェクションにより作出。C57BL/6N背景。 <a href="https://mus.brc.riken.jp/ja/wp-content/uploads/pdf/blc/01828_GB.pdf">Genetic Background</a> CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), SV40 nls, phage P1 Cre recombinase B（1〜3か月） RBRC01828 国立大学法人大阪大学 B (1-3 months)